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November 24, 2003

British Journal Recommends Immunization for Patients with Bleeding Disorders

The British journal Haemophilia outlined investigators' recommendations appropriate for patients with bleeding disorders, saying that the recommendations are different than those for people without bleeding disorders. The difference lies in the risk of hematoma formation at the vaccination site and the “unusual infective risks associate with the potential, and past, exposure to blood products,” said the report.

“Most vaccinations can be given subcutaneously and this should be the preferred route,” said one of the report's collaborators. “All routine childhood vaccinations should be given at the appropriate time. All patients with bleeding disorders should be vaccinated against hepatitis A and B. HIV positive patients should receive annual influenza vaccinations and should avoid the oral polio, oral typhoid, BCG and yellow fever vaccines.”

NHF's Medical and Scientific Advisory Council (MASAC) recommends children with bleeding disorders should receive a hepatits B at birth or at the time of diagnosis, and primary immune response should be documented. MASAC also recommends that all individuals two years or older who are hepatitis A virus seronegative should receive a hepatitis A vaccine.

The study can be found in Haemophilia , 2003;9(5)541-46.

Source: “Recommended Immunization of Patients with Bleeding Disorders Outlined.” Health & Medicine Week, November 24, 2003.

MASAC Document #151: http://www.hemophilia.org/programs/masac/masac151.htm

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